Ageing answers no longer a hard cell


Judith Campisi at the Future of Experimental Medicine Conference.

The holy grail of healthy old age may lie in the riddle of cells that stop cancer and hasten age at the same time.

Professor Judith Campisi, the head of research labs at San Francisco’s Buck Institute for Research on Ageing and the Lawrence Berkeley National Laboratory, presented this research at our Inflammation in Disease and Ageing conference in Manly.

Continue reading

Surfing at 85 – The genetics of healthy ageing and cancer

Centenary Institute We’re living longer. That means that we’re all at greater risk of cancer and we’ll all suffer from bone loss. And for many of us, our final years will be difficult.

Josef Penninger plans to change all that. His vision is of a future where we can safely surf and live active lives at 85 years of age without fear of fracture, cancer or any of the other scourges of ageing.

Continue reading

Young researchers fight cancer

  • How does melanoma move and spread?
  • How do our genes cause leukaemia?
  • And is shooting the messenger an effective treatment for melanoma?

Dr Kimberly Beaumont (centre) was one of our researchers awarded a grant.

Three researchers from the Centenary Institute and the University of Sydney have just been awarded an Early Career Fellowship by the Cancer Institute NSW to find the answers to these questions.

When dealing with the deadly form of skin cancer known as melanoma, shooting the messenger for once may turn out to be an effective strategy.

Continue reading

Starving cells may control melanoma

Could we treat melanoma by cutting off its food source?

jeff holst melanoma

Dr Jeff Holst (left) with colleague at Centenary Institute.

The latest research from Sydney’s Centenary Institute and the University of Sydney suggests we could.

Last year the researchers showed they could starve prostate cancer. Now a further discovery opens up the prospect of a new class of drugs that could work across a range of cancers including melanoma.

Continue reading

What does pain look like? How does the brain develop and grow?

The art of science: a network of nerve cells and a neural sunrise, captured under the microscope

lovelaceNeural spiderwebs – unlocking the secrets of low level laser irradiation for pain therapy

This stunning image shows a network of the nerve cells which carry sensory information from the world to your spinal cord and brain.

A fluorescent dye highlights the fine nerve fibres, which reach out to carry signals from one nerve cell to the next.

Continue reading

Caffeine Hit: Australian Made Energy Strips Concern Centenary Institute Cardiologist

Caffeine strips cardiovascular

Energy strips pose a cardiovascular concern to health experts.

New caffeine-laced energy strips that have recently hit Australian shelves are a major concern for Centenary Institute Cardiologist, Professor Chris Semsarian.

“Caffeine can increase your heart rate, it can increase your blood pressure, it can also increase the thickness of the blood in your blood vessels and that can lead to stroke,” Professor Semsarian said.

Continue reading

Tracking cancer at a thousand cells a second

Centenary InstituteThe Cancer Institute NSW has pitched in half a million dollars towards operating a biochemical tracking machine which will form the centrepiece of one of Sydney’s newest research centres.

The Ramaciotti Centre for Human Systems Biology, opening in 2014, will be home to Australia’s first CyTOF (cytometry by time of flight) mass spectrometer which can follow up to 100 different cellular processes simultaneously in a thousand cells each second.

Continue reading

Collaboration key to fighting diabetes

DiabetesThis week we reflect on the 2013 World Diabetes Congress (WDC) that was held in Melbourne between the 2-6 December. It was the biggest medical conference that’s ever been held in Australia, with over 10,000 delegates from over 130 countries, including world experts in science and health, diabetes sufferers, and their carers from all around the globe.

Not to miss out, a team of our diabetes and liver researchers from Centenary Institute presented some of their latest discoveries and listened to other experts in the field.

Continue reading

What’s the chance? Creative statistics revealing how we inherit diseases

Lawrence Creative Prize

Dr Jian Yang, courtesy of University of Queensland News.

Centenary Institute’s 2012 Lawrence Creative Prize winner, Dr Jian Yang, has been awarded a prestigious $1.2 million fellowship to continue his work using maths to unlock the mysteries around why some people are more susceptible to disease than others.

The computational biologist from the University of Queensland won the 2012 Centenary prize for his work developing statistical software to analyse genetic data in a novel way, taking the whole genome into account, not just the genetic variant associated with the disease.

And that is exactly the type of work the Lawrence Creative Prize is developed to foster.

Continue reading