Dr Nick Shackel, Associate Faculty, Liver Cell Biology, Liver Injury & Cancer. Photo by Kat Finch.
Dr Shackel studies the genes that are triggered when hepatitis strikes. He hopes his work will lead to a better and earlier understanding of the likely course of the disease in individual patients.
Hepatitis is an inflammation of the liver caused by infection with a virus. The virus types B and C that lead to chronic conditions are the most common causes of liver scarring or cirrhosis and of liver cancer. It is typically diagnosed after people visit their GPs complaining of extreme tiredness and is picked up through a routine blood test, which can even distinguish the type.
Dr Devanshi Seth, Group Leader, Alcoholic Liver Disease, Liver Injury & Cancer
Centenary’s Dr Devanshi Seth, a researcher who works in the liver lab and who also works at RPA’s Drug Health Services has given an in-depth interview about her work on heavy drinking and liver cirrhosis in the online magazine femail.com.au.
Dr Devanshi and her colleagues are soon to start testing the genes of hundreds of Sydney-siders and thousands of others across six countries with the support of the grant from the US National Institute on Alcohol Abuse and Alcoholism (NIAAA), part of the National Institutes of Health (NIH).
The US government is investing $2.5 million in a Sydney-based study to determine the role of genetics in alcoholic liver disease. The study, should lead to better diagnosis and treatment of the condition – a silent epidemic that costs $3.8 billion a year in Australia alone.